AI May Detect Alzheimer's Years Before Diagnosis AI May Detect Alzheimer's Years Before Diagnosis

Onset of Alzheimer's disease occurs years before appearance of clinical symptoms. Artificial intelligence (AI) using a sophisticated PET scan algorithm facilitates early detection and diagnosis.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Psychiatry News Source Type: news

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CONCLUSION: There are global and regional variations in annual accumulation rate at the predementia stage of Alzheimer's disease. When taken into account, the sample size in anti-amyloid trials can be substantially reduced. Critically, treated and placebo groups should be matched for BL SUVRGM. PMID: 30420035 [PubMed - in process]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
We present a comparison of three methods for estimating total intracranial volume to assess their robustness and correct the brain str ucture volumes using the residual method and the proportional (normalization by division) method. We then evaluated the distribution of brain structure volumes over the entire ADNI database before and after accounting for multiple covariates such as total intracranial volume, scanner field strength, sex, and age using two techniques: (a) Zscapes, a panoramic visualization technique to analyze the entire database and (b) empirical cumulative distributions functions. The results from this stu...
Source: Human Brain Mapping - Category: Neurology Authors: Tags: RESEARCH ARTICLE Source Type: research
The invention from Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) provides a non-invasive, painless means for measuring microanatomical features of Nerve and Axon Diameter Distribution (ADD) to image the Central and Peripheral Nervous Systems (CNS and PNS). ADD is altered in abnormal development (e.g., autism), in neurodegenerative processes (e.g., aging, alcoholism, Alzheimer ’s disease) and diseases such as ALS (Lou Gehrig’s disease). U.S. patent 7,643,863, related to this invention, consists of a novel diffusion Magnetic Resonance Imaging (MRI) experiment and mod...
Source: NIH OTT Licensing Opportunities - Category: Research Authors: Source Type: research
TUESDAY, Nov. 13, 2018 -- Fluorine 18 (18F) fluorodeoxyglucose (FDG) positron emission tomography (PET) of the brain can be used to develop a deep learning algorithm for early prediction of Alzheimer's disease (AD) that has high specificity and...
Source: - Pharma News - Category: Pharmaceuticals Source Type: news
In conclusion, our data support that weight loss negatively confounds the association between late-life obesity and brain atrophy. The obesity paradox on AD risk might be explained by reverse causation. PMID: 30410669 [PubMed]
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
Authors: Cassani R, Estarellas M, San-Martin R, Fraga FJ, Falk TH Abstract Alzheimer's disease (AD) is a neurodegenerative disorder that accounts for nearly 70% of the more than 46 million dementia cases estimated worldwide. Although there is no cure for AD, early diagnosis and an accurate characterization of the disease progression can improve the quality of life of AD patients and their caregivers. Currently, AD diagnosis is carried out using standardized mental status examinations, which are commonly assisted by expensive neuroimaging scans and invasive laboratory tests, thus rendering the diagnosis time consumi...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
It's long been known that Alzheimer's patients often retain musical memories, even when they can't remember names, faces or places. Canadian researchers say brain scans have helped them understand why.
Source: CBC | Health - Category: Consumer Health News Tags: News/Health Source Type: news
ConclusionBy using fluorine 18 fluorodeoxyglucose PET of the brain, a deep learning algorithm developed for early prediction of Alzheimer disease achieved 82% specificity at 100% sensitivity, an average of 75.8 months prior to the final diagnosis.Alzheimer's Clock Draw Test -- Detect the Signs of Alzheimer's EarlyCan An Undetected Urinary Tract Infection Can Kill an Alzheimer's PatientAlzheimer's Care Using the Brain to Create HappinessLearn More from Our Award Winning Knowledge Base - Topics PagesMy mom has dementia and is meanHow do you talk and communicate effectively with a dementia patientHow to live with someone who ...
Source: Alzheimer's Reading Room, The - Category: Neurology Tags: alzheimers alzheimers research Artificial intelligence brain brain imaging health improve diagnosis predict alzheimer science Source Type: blogs
A deep learning algorithm trained to analyze brain scans accurately predicted who would develop Alzheimer's more than 6 years before diagnosis.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
Lung cancer is the most frequent type of cancer across genders and the most common reason for cancer-related death worldwide [1]. Hybrid positron emission tomography/computed tomography (PET/CT) using 18F-fluorodeoxyglucose (FDG) is an established imaging method for the staging of patients with lung cancer [2]. Recently, the use of artificial intelligence and more specifically deep learning has produced promising results in various applications in medicine, including automated skin cancer detection [3] or automated Alzheimer disease detection based on FDG-PET data [4].
Source: Lung Cancer - Category: Cancer & Oncology Authors: Source Type: research
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