A Cross-Country Comparison of Rivaroxaban Spontaneous Adverse Event Reports and Concomitant Medicine Use with the Potential to Increase the Risk of Harm

Conclusion A large proportion of adverse event reports for rivaroxaban were associated with use of concomitant medicines, which may have increased the risk of adverse events—in particular, haemorrhage. Increased awareness of a patient’s comorbidity and associated medicine use is needed when rivaroxaban is used in clinical practice.
Source: Drug Safety - Category: Drugs & Pharmacology Source Type: research