Evaluation of the effects of pregabalin on chondrocyte proliferation and CHAD, HIF-1 α, and COL2A1 gene expression.

Conclusions: Further studies need to be conducted with more participants to prove that there is a negative correlation between extracellular matrix formation and PGB administration. Our preliminary data show that even at low doses and over short-term administration, PGB may affect chondrocyte cells at the gene-expression level. PMID: 30393488 [PubMed]
Source: Archives of Medical Science - Category: Biomedical Science Tags: Arch Med Sci Source Type: research