Incidence and Risk Factors of Dry Eye in a Spanish Adult Population: 11-Year Follow-Up From the Salnés Eye Study

Purpose:
To estimate the incidence of dry eye (DE) and to evaluate risk factors in an adult cohort in Spain.
Methods:
The Salnés Eye Study (SES) was a cross-sectional population-based study of 654 subjects conducted from 2005 to 2006. After 11 years, 264 individuals (65.8% response rate) participated in SES 2. The incidence cohort consisted of 209 subjects not diagnosed with DE in SES 1 [mean age (SD) 67.6 years (±10.1), range: 51–92, women 69.4%]. DE was defined as the simultaneous presence of symptoms and at least 1 sign. A Schirmer test score ≤5 mm, tear film breakup time ≤10 seconds, rose bengal staining ≥3, and fluorescein staining ≥1 were considered indicative of signs. Poisson regression models were performed to evaluate risk factors.
Results:
The 11-year incidence of DE was 25.4% (95% confidence interval, 19.5–31.3) and that of symptoms was 31.6% (confidence interval, 25.4–37.8). DE incidence was significantly associated with age (P

Source: Cornea - November 6, 2018 Category: Opthalmology Tags: Clinical Science Source Type: research