Melanoma arising in a chronic pressure ulcer

International Wound Journal, EarlyView.
Source: International Wound Journal - Category: Surgery Authors: Source Type: research

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Publication date: November 2019Source: Fish &Shellfish Immunology, Volume 94Author(s): Yaoguo Li, Shengzhen Jin, Xin Zhao, Hong Luo, Rui Li, Dongfang Li, Tiaoyi XiaoAbstractMDA5 is a cytoplasmic viral double-stranded RNA recognition receptor that plays a pivotal role in the aquatic animal innate immune system. To decipher the role of MDA5 of Squaliobarbus curriculus (ScMDA5) in the immune response, full-length cDNA of ScMDA5 was cloned using the RACE technology, mRNA and protein expression levels of ScMDA5 signalling pathway members in response to stimulation were detected and effects of overexpression of ScMDA5 on the...
Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
Conference abstracts
Source: The Aspergillus Website - updates - Category: Respiratory Medicine Authors: Source Type: news
Authors: Putzer D, Schullian P, Bale R Abstract Standard treatment of melanoma has been evolving rapidly over the last decade, with novel treatment approaches improving therapeutic outcome not only in early-stage disease but also in advanced stage metastatic patients. Despite the improvement of systemic therapy outcomes, the current treatment guidelines reflect the fact that locoregional treatment approaches can be beneficial in patients suffering from oligometastatic disease. Minimally invasive ablation techniques have been established as a therapeutic cornerstone in the management of liver tumors, representing a ...
Source: International Journal of Hyperthermia - Category: Internal Medicine Tags: Int J Hyperthermia Source Type: research
Inguinal lymphadenectomy (ILND) for melanoma is associated with a number of complications including seroma, surgical-site infection (SSI) and lymphedema. Incisional Negative Pressure Wound Therapy (iNPWT) has shown promising results in preventing postoperative morbidity across a wide variety of surgical procedures, but has yet to be investigated in patients undergoing ILND for melanoma.
Source: Journal of Plastic, Reconstructive and Aesthetic Surgery - Category: Cosmetic Surgery Authors: Source Type: research
Radical inguinal lymphadenectomy (ILND) for metastatic melanoma is associated with a high complication rate. Seroma is often the first postoperative complication, followed by prolonged wound healing sometimes ...
Source: Trials - Category: General Medicine Authors: Tags: Study protocol Source Type: research
This report describes a case of amelanotic melanoma of the foot initially diagnosed and treated as a pressure ulcer.Wounds
Source: Medscape Today Headlines - Category: Consumer Health News Tags: General Surgery Journal Article Source Type: news
CONCLUSIONS: Physicians must remain highly cautious of ulcerated lesions of the foot and may consider epidermal fractional skin grafting as a valid therapeutic option in case of postsurgical wounds resulting from wide local excision of malignant melanomas. PMID: 29718821 [PubMed - in process]
Source: Wounds - Category: General Medicine Tags: Wounds Source Type: research
We describe the case of a child born with a GN who developed a metastatic melanoma early in life, despite early commencement of resection of the nevus. This is contrasted against a second case of a child in which a more radical management was conducted. Despite early commencement of serial resection of the GN, the first child in this series died of metastatic melanoma prior to complete excision of the nevus. With the second child, radical excision combined with the use of Integra ™ and negative pressure wound therapy allowed total removal of the GN within the first 6 months of life.
Source: Pediatric Surgery International - Category: Surgery Source Type: research
ConclusionsThe medialis pedis flap may be considered a useful flap for the reconstruction of soft tissue defects smaller than 5 cm in the weight bearing heel.
Source: Microsurgery - Category: Surgery Authors: Tags: CLINICAL ARTICLE Source Type: research
Abstract Melanoma in darker‐pigmented individuals often develops in an acral lentiginous fashion on the foot. After surgical removal of a tumor at this site, repair of the wound can be challenging. This is because there is an insufficient local skin pool and lack of mobility of the skin in this area. Moreover, functional aspects such as walking and weight bearing should be considered. We performed a combination treatment of negative pressure wound therapy (NPWT) and punch grafting on 15 patients, after wide excision of acral lentiginous melanomas on the foot, and compared these to 26 patients who underwent either seconda...
Source: The Journal of Dermatology - Category: Dermatology Authors: Tags: Original Article Source Type: research
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