Erythrophages do not develop when lumbar CSF and blood samples are mixed in vitro

ConclusionsWe did not find evidence for an in vitro erythrophagocytosis after a mimicked traumatic lumbar puncture. Therefore, the occurrence of erythrophages in CSF cytology can be regarded as a reliable sign of an autochthonous bleeding in the subarachnoid space. Our results support the crucial role of CSF analysis in clinical practice in case of a suspected SAH but negative cerebral imaging.
Source: Fluids and Barriers of the CNS - Category: Neuroscience Source Type: research