Altered endotoxin responsiveness in healthy children with Down syndrome

Down syndrome (DS) is the most common syndromic immunodeficiency with an increased risk of infection, mortality from sepsis, and autoinflammation. Innate immune function is altered in DS and therefore we exami...

Source: BMC Immunology - November 3, 2018 Category: Allergy & Immunology Authors: Dean Huggard, Fiona McGrane, Niamh Lagan, Edna Roche, Joanne Balfe, Timothy Ronan Leahy, Orla Franklin, Ana Moreno, Ashanty M. Melo, Derek G. Doherty and Eleanor J. Molloy Tags: Research article Source Type: research