Adrenomedullin and glucagon-like peptide-1 have additive effects on food intake in mice

In conclusion, we demonstrate additive anorectic effects of ADM and GLP-1, and that GLP-1 co-administration prevents ADM-induced impairment of glucose tolerance, suggesting that ADM could be potential anti-obesity target when combined with GLP-1 agonist therapy.Graphical abstractAdrenomedullin and GLP-1 shows additive effects on acute food intake in mice.
Source: Biomedicine and Pharmacotherapy - Category: Drugs & Pharmacology Source Type: research