CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

Conclusions
Inflammation-associated angiogenesis is promoted by CCL2-dependent monocytes during fibrosis progression. Innovative in vivo µCT methodology can accurately monitor angiogenesis and antiangiogenic therapy effects in experimental liver fibrosis.

Source: Gut - October 31, 2014 Category: Gastroenterology Authors: Ehling, J., Bartneck, M., Wei, X., Gremse, F., Fech, V., Mockel, D., Baeck, C., Hittatiya, K., Eulberg, D., Luedde, T., Kiessling, F., Trautwein, C., Lammers, T., Tacke, F. Tags: Cirrhosis, Pancreas and biliary tract, Hepatic cancer Hepatology Source Type: research