Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease

Conclusions
IL-17A-induced HSP47 expression is involved in collagen I expression in ISEMFs, which might contribute to intestinal fibrosis in CD.

Source: Gut - October 31, 2014 Category: Gastroenterology Authors: Honzawa, Y., Nakase, H., Shiokawa, M., Yoshino, T., Imaeda, H., Matsuura, M., Kodama, Y., Ikeuchi, H., Andoh, A., Sakai, Y., Nagata, K., Chiba, T. Tags: Crohn's disease Inflammatory bowel disease Source Type: research