High ratio of measles-specific IgG/IgM associated with nodular pneumonia in vaccinated individuals

Measles is a highly contagious viral disease and was the cause of millions of deaths each year prior to the introduction of the measles vaccine. Since the introduction of the vaccine, the incidence of measles has dropped significantly (Rota et al., 2016). Immunity to measles was thought to be life-long (Panum, 1847), but it has been demonstrated that immunity wanes over time, regardless of whether immunity was acquired from a killed vaccine, live-attenuated vaccine, or natural infection (Rauh and Schmidt, 1965; Dai et al., 1991; Kremer et al., 2006).
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research