Validation of the French 3-year prognostic score using the Canadian Cystic Fibrosis registry

Studies of large CF populations using registry data are important to identify people at high risk for death. Nkam et al. published a prognostic score developed on French CF registry data to predict death or lung transplantation (LT) over a 3-year period in the adult CF population. The goal of our study was to validate the proposed tool using the Canadian CF registry. Using data between 2011 and 2014, a total of 2043 adult CF patients were included. We found that the French prognostic score was a good predictor of death or LT in the Canadian CF population (OR for each unit increase: 3.12, 95% CI: 2.74 –3.55; p value 

Source: Journal of Cystic Fibrosis - November 2, 2018 Category: Respiratory Medicine Authors: Ad èle Coriati, Jenna Sykes, Lionelle Nkam, Mounia N. Hocine, Pierre-Régis Burgel, Anne L. Stephenson Source Type: research