Insect Repellents: An Updated Review for the Clinician

Malaria, Zika virus, West Nile virus, Dengue fever, and Lyme disease are common causes of morbidity and mortality around the world. While arthropod bites may cause local inflammation and discomfort, a greater concern is the potential to develop deadly systemic infection. The use of insect repellents (IR) to prevent systemic infections constitutes a fundamental public health effort. Cost-effectiveness, availability, and high-efficacy against arthropod vectors are key characteristics of an ideal IR.
Source: Journal of the American Academy of Dermatology - Category: Dermatology Authors: Source Type: research

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CONCLUSIONS: Considering the impact of global climate change on the region, these findings can help to predict trends in dengue fever incidence.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
CONCLUSIONS We report the first documentation of Ae. fluviatilis in the municipality of Saboeiro, northeastern Brazil. It is important to conduct additional entomological surveys to characterize the local Culicidae fauna. Ignoring the presence and dispersion of this vector could be a public health risk.
Source: Revista da Sociedade Brasileira de Medicina Tropical - Category: Tropical Medicine Source Type: research
In this study, after implementing the intervention using the PRECEDE educational program, asignificant difference was found between the intervention and control groups in the mean scores for predisposing factors (knowledge and attitude) (P
Source: Pathogens and Global Health - Category: International Medicine & Public Health Tags: Pathog Glob Health Source Type: research
Publication date: Available online 20 February 2019Source: Biosensors and BioelectronicsAuthor(s): Sanghyun Lee, Wonhyung Lee, Hojin Kim, Pan Kee Bae, Jaechan Park, Joonwon KimAbstractIn the study, we describe an oscillatory flow-assisted efficient target enrichment method by using a particle-based microarray device. Periodic oscillating flow effectively increased the mixing and binding performance between the target molecules in the sample solution and surface functionalized microparticles. Particles were trapped, secured, and released with an elastic microvalve structure operated via differences in the flow conditions. S...
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
Experts at a lab in Terni, Italy, believe that gene-editing the insect's DNA to make them more male is the answer. This is because only females have mouths big enough to bite human beings.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
ConclusionNMR-based metabolomics combined with supervised multivariate data analysis is a powerful strategy for the identification of bioactive metabolites in plant extracts. Moreover, combination of statistical total correlation spectroscopy with 2D NMR allowed a detailed analysis of different triterpenes, overcoming the challenge posed by their structure similarity and coalescence in the aliphatic region.
Source: Metabolomics - Category: Biology Source Type: research
This study was undertaken to assess the evolution of antibodies to the dominant surface antigens of Plasmodium vivax and P. falciparum following controlled human malaria infection (CHMI) in malaria-naive individuals. Serum samples from malaria-naive adults, collected before and after CHMI with either P. vivax (n = 18) or P. falciparum (n = 18), were tested for the presence of antibodies to the circumsporozoite protein (CSP) and the 42-kDa fragment of merozoite surface protein 1 (MSP-142) of P. vivax and P. falciparum using an enzyme-linked immunosorbent assay (ELISA). Approximately 1 month following CHMI with either P. viv...
Source: Infection and Immunity - Category: Infectious Diseases Authors: Tags: Fungal and Parasitic Infections Source Type: research
AbstractDengue disease is characterized by a marked decrease in platelet count, which is life threatening. In the present study, we investigated the antiviral activity of an aqueous extract ofCarica papaya leaves (PLE) against dengue virus (DENV) and its effect on platelet augmentation. The anti-dengue activity of PLE in DENV-infected THP-1 cells was examined by immunoblotting and flow cytometry. The effect of PLE on erythrocyte damage was investigated using hemolytic and anti-hemolytic assays. Virus-infected THP-1 cells were assayed for IFN- α secretion. The effect of PLE on platelet augmentation in rats with cyclop...
Source: Archives of Virology - Category: Virology Source Type: research
This study describes an impedimetric electrochemical DNA biosensor for label-free detection of zika virus. Disposable electrodes were fabricated by thermal evaporation on polyethylene terephthalate substrates covered with a nanometric gold layer manufactured in three-contact configurations. The disposable, evaporated electrodes were morphologically characterized by atomic force microscopy and scanning electron microscopy. The electrode surface was characterized by electroanalytical techniques. Genetic sequences of primers and complementary capture probes were designed based on analysis of the zika and dengue virus genomes....
Source: Biosensors and Bioelectronics - Category: Biotechnology Source Type: research
For most of us, springtime marks the return of life to a dreary landscape, bringing birdsong, trees in bud, and daffodils in bloom. But if you work for the Centers for Disease Control and Prevention (CDC), the coming of spring means the return of nasty diseases spread by ticks and mosquitoes. The killjoys at CDC celebrated the end of winter with a bummer of a paper showing that infections spread by ticks doubled in the United States from 2004 to 2016. (Tick populations have exploded in recent decades, perhaps due to climate change and loss of biodiversity.) Lyme disease The most common infection spread by ticks in the US i...
Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Health Infectious diseases Source Type: blogs
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