Vitamin and mineral supplementation for preventing dementia or delaying cognitive decline in people with mild cognitive impairment.
CONCLUSIONS: The evidence on vitamin and mineral supplements as treatments for MCI is very limited. Three years of treatment with high-dose vitamin E probably does not reduce the risk of progression to dementia, but we have no data on this outcome for other supplements. Only B vitamins have been assessed in more than one RCT. There is no evidence for beneficial effects on cognition of supplementation with B vitamins for six to 24 months. Evidence from a single study of a reduced rate of brain atrophy in participants taking vitamin B and a beneficial effect of vitamin B on episodic memory in those with higher tHcy at baseline warrants attempted replication.
PMID: 30383288 [PubMed - as supplied by publisher]
Source: Cochrane Database of Systematic Reviews - Category: General Medicine Authors: McCleery J, Abraham RP, Denton DA, Rutjes AW, Chong LY, Al-Assaf AS, Griffith DJ, Rafeeq S, Yaman H, Malik MA, Di Nisio M, MartÃnez G, Vernooij RW, Tabet N Tags: Cochrane Database Syst Rev Source Type: research
More News: Alzheimer's | Brain | Chromium | Databases & Libraries | Dementia | Folic Acid | General Medicine | Information Technology | Minerals | Neurology | Science | Study | Vitamin B | Vitamin B9 | Vitamin C | Vitamin E | Vitamins