Infectious keratitis: microbiological review of 297 cases.

Infectious keratitis: microbiological review of 297 cases. Jpn J Infect Dis. 2018 Oct 31;: Authors: Tena D, Rodríguez N, Toribio L, González-Praetorius A Abstract Infectious keratitis is a serious ocular infection that can lead to loss of vision. The aim of the study was to investigate the microbiological characteristics of this infection at the University Hospital of Guadalajara (Spain). We retrospectively reviewed all cases diagnosed between January 2010 and December 2016. During the 7-year study period, 297 corneal scrapes corresponding to 298 patients were performed. Antibiotic treatment previous to the culture occurred in 59 cases (19.5%). Contact lens wear was the most common risk factor (33.2%). Bacterial keratitis accounted for 64.6% of cases, viral keratitis 3.4% and fungal keratitis 1%. A total of 241 bacteria were identified. Gram-positive isolates represented 87.1% and gram-negative 12.7%. Coagulase-negative Staphylococcus were the most common organisms isolated (30.3%). When gram-positive organisms were analyzed, the sensitivity percentages for vancomycin, levofloxacin, gentamicin and tobramicin were: 99.4%, 84.6%, 87.9% and 88.3% respectively. For the gram-negative organisms, the sensitivity percentages for ceftazidime, ciprofloxacin, gentamicin and tobramicin were: 83.3%, 93.5%, 96.3% and 100% respectively. Our study revealed a great predominance of gram-positive organisms. We suggest empirically treating bacterial k...
Source: Japanese Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Jpn J Infect Dis Source Type: research