Treating and Preventing Malaria Acquired Abroad

(MedPage Today) -- With global progress against malaria stalling, U.S. physicians and patients need to be aware
Source: MedPage Today Infectious Disease - Category: Infectious Diseases Source Type: news

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This study shows that the magnitude of the host transcriptional response can differ markedly from related parasites with different virulence, and it enables a better understanding of the molecular interactions taking place between hosts and parasites. PMID: 32469658 [PubMed - as supplied by publisher]
Source: The American Naturalist - Category: Biology Authors: Tags: Am Nat Source Type: research
[Los aptámeros como novedosa herramienta diagnóstica y terapéutica y su potencial uso en parasitología]. Biomedica. 2020 May 01;40(Supl. 1):148-165 Authors: Ospina JD Abstract Los aptámeros son secuencias de ADN o ARN de cadena sencilla que adoptan la forma de estructuras tridimensionales únicas, lo cual les permite reconocer un blanco específico con gran afinidad. Sus usos potenciales abarcan, entre otros, el diagnóstico de enfermedades, el desarrollo de nuevos agentes terapéuticos, la detección de riesgos alimentarios, la producci&...
Source: Biomedica : Revista del Instituto Nacional de Salud - Category: International Medicine & Public Health Tags: Biomedica Source Type: research
Sanofi has temporarily stopped recruiting new COVID-19 patients for two clinical trials on hydroxychloroquine and will no longer supply the anti-malaria drug to treat COVID-19 until concerns about safety are cleared up, it said on Friday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
Traveling man: the Goodwill Ambassador shares a joke with two residents of a leprosarium in Krantau, Uzbekistan during a visit in 2013.By External SourceMay 29 2020 (IPS-Partners)   Warm greetings from Sasakawa Health Foundation in Tokyo. The 100th Issue of the WHO Goodwill Ambassador’s Newsletter has been published. Read special interviews with the Goodwill Ambassador and the UN Special Rapporteur on leprosy, and check out the Timeline of all that has happened since the first issue. My Journey Continues I started this newsletter in April 2003 to share information about the fight against leprosy. This marks th...
Source: IPS Inter Press Service - Health - Category: International Medicine & Public Health Authors: Tags: Health Source Type: news
U.S. hospitals said they have pulled way back on the use of hydroxychloroquine, the malaria drug touted by President Donald Trump as a COVID-19 treatment, after several studies suggested it is not effective and may pose significant risks.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
(Ehime University) An international collaborative team from PROS Ehime University and CellFee Science, Japan; the Walter and Eliza Hall Institute, Australia; Pasteur Institute, France; and Foundation for Innovative New Diagnostics, Switzerland developed a new diagnostic blood test which detects recent exposure to 'vivax' malaria. The new test can also identify people who may harbor dormant liver-stage malaria parasites, which can cause illness. This new diagnostic approach has the potential to enhance malaria surveillance and accelerate elimination.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Plasmodium falciparum is causative agent of human malaria. Sixty percent of mRNAs from its extremely AT-rich (81%) genome harbor long polyadenosine (polyA) runs within their ORFs, distinguishing the parasite from its hosts and other sequenced organisms. Recent studies indicate polyA runs cause ribosome stalling and frameshifting, triggering mRNA surveillance pathways and attenuating protein synthesis. Here, we show that theP. falciparum is an exception to this rule. We demonstrate that both endogenous genes and reporter sequences containing long polyA runs are efficiently and accurately translated inP. falciparum cells. We...
Source: eLife - Category: Biomedical Science Tags: Biochemistry and Chemical Biology Cell Biology Source Type: research
The multicopy var gene family of Plasmodium falciparum is of crucial importance for pathogenesis and antigenic variation. So far only var2csa, the var gene responsible for placental malaria, was found to be highl...
Source: Malaria Journal - Category: Infectious Diseases Authors: Tags: Research Source Type: research
Veterans Affairs Secretary Robert Wilkie says his department has all but stopped use of an unproven malaria drug on veterans with COVID-19
Source: ABC News: Health - Category: Consumer Health News Tags: Health Source Type: news
A university in Germany has suspended a clinical study using the anti-malaria drug hydroxychloroquine for COVID-19, Spiegel Online reported on Thursday, after the World Health Organisation decided this week to pause a large trial over safety concerns.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news
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