Screening of blood-activating active components from Danshen–Honghua herbal pair by spectrum-effect relationship analysis

ConclusionsDH herbal pair showed strong blood-activating effect on blood stasis rat through regulating the parameters involved in haemorheology and plasma coagulation system. Four active compounds, caffeic acid, salvianolic acid B, hydroxysafflor yellow A and lithospermate acid predicted by spectrum-effect relationship analysis had good blood-activating effect. Therefore, spectrum-effect relationship analysis is an effective approach for seeking active components in herbal pairs.Graphical abstract
Source: Phytomedicine - Category: Drugs & Pharmacology Source Type: research