Chondrocytes cultured in silk-based biomaterials maintain function and cell morphology.

CONCLUSION:: Regenerated silk fibroin film was found to be an excellent biomaterial with good cytocompatibility for chondrocytes, because these cells remained functional and maintained normal cell morphology when cultured in silk-based biomaterials. These results suggest that silk-based chondrocyte biomaterial complexes may provide a feasible and functional biomaterial for repairing clinical cartilage defects.
PMID: 30376753 [PubMed - as supplied by publisher]

Source: The International Journal of Artificial Organs - October 30, 2018 Category: Transplant Surgery Authors: Ni Y, Jiang Y, Wang K, Shao Z, Chen X, Sun S, Yu H, Li W Tags: Int J Artif Organs Source Type: research