Investigation of unbound colistin A and B in clinical samples using a mass spectrometry method.
The objectives of this study were to develop a method to isolate unbound colistin in clinical samples by ultrafiltration and to quantify it. The association between unbound colistin and biological parameters (total protein, albumin, alpha-1-acid glycoprotein, and creatinine) was investigated.
Source: International Journal of Antimicrobial Agents - Category: Drugs & Pharmacology Authors: D. Fage, G. Deprez, F. Wolff, M. Hites, F. Jacobs, F. Van Bambeke, F. Cotton Source Type: research
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