Depolarization versus repolarization abnormality underlying inferolateral J wave syndromes – new concepts in sudden cardiac death with apparently normal hearts

Early repolarization indicates a distinct electrocardiographic phenotype affecting the junction between the QRS complex and the ST segment in inferolateral leads (inferolateral J-Wave Syndromes). It has been considered a benign electrocardiographic variant for decades, but recent clinical studies have demonstrated its arrhythmogenicity in a small subset, supported by experimental studies showing transmural dispersion of repolarization. Here, we review the current knowledge and the issues of risk stratification which limit clinical management.
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research