Depolarization versus repolarization abnormality underlying inferolateral J wave syndromes – new concepts in sudden cardiac death with apparently normal hearts
Early repolarization indicates a distinct electrocardiographic phenotype affecting the junction between the QRS complex and the ST segment in inferolateral leads (inferolateral J-Wave Syndromes). It has been considered a benign electrocardiographic variant for decades, but recent clinical studies have demonstrated its arrhythmogenicity in a small subset, supported by experimental studies showing transmural dispersion of repolarization. Here, we review the current knowledge and the issues of risk stratification which limit clinical management.
Source: Heart Rhythm - Category: Cardiology Authors: Michel Ha ïssaguerre, Koonlawee Nademanee, Mélèze Hocini, Ghassen Cheniti, Josselin Duchateau, Antonio Frontera, Frédéric Sacher, Nicolas Derval, Arnaud Denis, Thomas Pambrun, Rémi Dubois, Pierre Jaïs, David Benoist, Richard D. Walton, Akihiko Noga Source Type: research