Squamous cell carcinoma arising from mature cystic teratoma of the ovary: a challenging question for gynecologic oncologists

Mature cystic teratoma [MCT] of the ovary arises from germ cells by failure of meiosis II or from a premeiotic cell in which meiosis I has failed, and it might consist of multiple cell types derived from one or more of the three germ layers (ectoderm, mesoderm and endoderm) ( Surti et al., 1990; Hackethal et al., 2008). It may occur at any age, with highest peak between 30 and 40 years (Nogales et al., 2003; Comerci et al., 1994; Morgante et al., 1998; Rim et al., 2006; Goudeli et al., 2016). The incidence of ovarian MCTs is approximately 1.2 –14.2 cases per 100.000 people per year (Hackethal et al., 2008).
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research