A systematic review examining clinical markers and biomarkers of analgesic response to radiotherapy for cancer-induced bone pain

A consequence of the increasing number of patients being diagnosed and living with cancer is that more patients also live with disseminated disease. These patients will often need palliative care input at some point in their disease trajectory, resulting in an increased burden on palliative care services. Of all organs primary cancers spread to, bone is one of the most common. Bone metastases are associated with pain in up to 50% of patients, termed cancer-induced bone pain (CIBP). (Coleman, 1997; Coleman, 2006; Mercadante, 1997) CIBP adversely affects quality of life, therefore treatment of CIBP is of great importance.( Cramarossa et al., 2013)
Source: Critical Reviews in Oncology Hematology - Category: Cancer & Oncology Authors: Source Type: research