Gold-Based Nanoparticles Systems in Phototherapy - Current Strategies.

CONCLUSION: In this work, we show numerous medically and chemically important development strategies of hybrid types of drugs which can be used in phototherapy. These systems have a high affinity to the tumor cells surface proteins which transport the nanoparticles directly into a cell. The application of functionalized metallic nanoparticles in phototherapy improved photophysical properties, lowered cytotoxicity of common used photosensitizers and facilitated the development of the third generation photosensitizers. Furthermore, this type of nanoparticles could also be used as a cytostatic drug carrier in the chemo or combined anticancer therapies. PMID: 30378476 [PubMed - as supplied by publisher]
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research