Cost-Effectiveness Analysis of Genotype-Guided Treatment Allocation in Patients with Alcohol Use Disorders Using Naltrexone or Acamprosate, Using a Modeling Approach

In conclusion, pharmacogenetic treatment allocation of AUD patients to naltrexone, based onOPRM1 genotype, can be a cost-effective strategy, and could have potential individual and societal benefits. However, more evidence on the impact of genotype-guided treatment allocation on relapse is needed to substantiate these conclusions, as there is contradictory evidence about the effectiveness ofOPRM1 genotyping.Eur Addict Res 2018;24:245 –254
Source: European Addiction Research - Category: Addiction Source Type: research

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Source: SafetyLit - Category: International Medicine & Public Health Tags: Alcohol and Other Drugs Source Type: news
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Source: Frontiers in Human Neuroscience - Category: Neuroscience Source Type: research
The word “bipolar” has become colloquially associated with anything that changes rapidly or is unpredictable: the weather, technology, sports teams, politics, or even a teenager’s attitude. But for roughly 46 million people worldwide, being “bipolar” is far more serious than typical unpredictability, mood swings, or temperamental behavior. And, when bipolar disorder is complicated by substance use disorder (SUD), the situation can become incredibly dangerous for the individual and those around them. Recognizing the symptoms of bipolar and the complicating factors of substance use disorder is c...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Addiction Alcoholism Bipolar Recovery Substance Abuse Addiction Recovery Bipolar Disorder Detox Dual Diagnosis World Bipolar Day Source Type: blogs
  Cannabis, weed, marijuana, pot. It goes by several names, but we all know what it smells like. As weed becomes more mainstream, we on the Not Crazy podcast want to know: Is marijuana really an effective treatment for anxiety? Is it just a coping mechanism? Or a vice? In today’s podcast, Gabe and Jackie look at the research and weigh out the evidence. They also interview Eileen Davidson, a rheumatoid arthritis patient who regularly uses marijuana as a medicine to see what she has to say. What’s your take? Tune in for an open-minded discussion about weed. (Transcript Available Below) SUBSCRIBE &REV...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Anxiety and Panic General Medications Not Crazy Podcast Source Type: blogs
We described trauma experienced by the National Consortium on Alcohol and Neurodevelopment in Adolescence (NCANDA) longitudinal sample (N = 831) participants and examined drinking over 4 years. We hypothesize that more traumatic events and PTSS will predict transition to moderate/heavy drinking.SummaryA total of 658 no/low drinkers at baseline were followed yearly for 4  years for transition to moderate/heavy drinking using logistic regression models. Youth were grouped by no trauma (n = 257), trauma (n = 348), and trauma with PTSS (n = 53). Those with traum...
Source: Current Addiction Reports - Category: Addiction Source Type: research
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Source: International Journal of Mental Health and Addiction - Category: Addiction Source Type: research
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Source: Psych Central - Category: Psychiatry Authors: Tags: Addictions Alcoholism Habits Substance Abuse Source Type: news
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Source: Substance Use and Misuse - Category: Addiction Tags: Subst Use Misuse Source Type: research
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Source: American Journal on Addictions - Category: Addiction Authors: Tags: Am J Addict Source Type: research
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