Depletion of Endogenous miRNA-378-3p Increases Peak Cell Density of CHO DP12 Cells and is Correlated with Elevated Levels of Ubiquitin Carboxyl-Terminal Hydrolase 14

This study highlights miR-378-3p as a novel engineering candidate for improving CHO cell growth. The use of subcellular fractionation also improved proteome coverage in the identification of novel miRNA targets.
Source: Journal of Biotechnology - Category: Biotechnology Source Type: research