What Contributes to the Success of Early Career Scientists? – A NIAID Look
At NIH, we are heavily invested in our workforce and in understanding the barriers they face. What characteristics do they share? How do they compete in the current hypercompetitive environment? When do they stop applying to NIH (drop out), even after receiving their first award? Staff from the National Institute of Allergy and Infectious Diseases (NIAID) delve into these questions in a paper published recently in PLOS ONE , whose findings I’d like to highlight today. Here, Drs. Patricia Haggerty and Matthew Fenton looked at factors that may contribute to the success of early-career investigators and if these factors affect all junior researchers equally. This analysis focused on a cohort of investigators who received their first NIH R01-equivalent research grant (referred to as R01-e) awards (which included R01s, program projects and cooperative agreements) specifically from NIAID between fiscal years 2003 and 2010 (n=1,496). By following their subsequent grant applications through 2016 (or through their final application, whichever came first), our colleagues tracked funding outcomes of this cohort of investigators – referred to as “Early NIH-funded Investigators” (ENI) in the paper. ENI who obtained another R01-e award (from any NIH research Institute) were referred to as “successful” or “funded” ENI, whereas those did not were referred to as “unfunded” ENI. As Table 1 shows, 57 percent of the cohort ENI were succ...
Conditions: Keratoconus; Dry Eye; Allergy Intervention: Drug: dexamethasone ophthalmic insert 0.4 mg, for intracanalicular use Sponsor: Illinois College of Optometry Not yet recruiting
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Drs Andrew Wilner and William Li discuss recent findings suggesting that many of the symptoms of SARS-CoV-2 -- stroke included -- may be due to underlying vascular pathology.Medscape Neurology
Conclusions: This real-world study confirms the high frequency of FGIDs in infants in France, and provides new information regarding the characteristics of FGID infants.
Molecules, Vol. 25, Pages 2622: Generation of High Affinity Anti-Peptide Polyclonal Antibodies Recognizing Goat αs1-Casein Molecules doi: 10.3390/molecules25112622 Authors: Aliah Zannierah Mohsin Rashidah Sukor Jinap Selamat Anis Shobirin Meor Hussin Intan Hakimah Ismail Nuzul Noorahya Jambari Farina Mustaffa-Kamal The chemical, technological and allergy properties of goat’s milk are significantly affected by the level of αs1-casein. Detection and quantification of αs1-casein requires high-specificity methods to overcome high-sequence similarity between this protein a...
Conclusions: Keeping a dog at home before and during pregnancy decreased the risk of food allergy in 1-year-old children. This effect was eliminated in case of having a cat, hamster, guinea pig, or rabbit. PMID: 32489363 [PubMed]
A review of FDA reports also shows notably higher rates of shingles in women among younger patients taking disease-modifying therapies for multiple sclerosis.Medscape Medical News
WebMD Chief Medical Officer John Whyte talks with Dr Deepak Bhatt about the ways COVID-19 puts heart disease patients at risk and also causes new heart problems.WebMD
Condition: Peanut Allergy Interventions: Dietary Supplement: High dose of peanuts; Dietary Supplement: Low dose of peanuts Sponsor: Medical University of Warsaw Not yet recruiting
Condition: Temple Hollowing Intervention: Device: JUVÉDERM VOLUMA® XC Sponsor: Allergan Recruiting