Impact of Primary Disease Nature in the Development of De Novo Donor-Specific Antibodies After Kidney Transplant and the Risk of Acute Rejection.

CONCLUSIONS: No associations were shown between the frequency of de novo donor-specific antibody development after kidney transplant and the nature of the primary disease (autoimmune vs nonautoimmune). Detection of de novo donor-specific antibodies was associated with higher rates of biopsy-proven acute rejection among patients with nonautoimmune primary disease. PMID: 30373505 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/30373505?dopt=Abstract

Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - October 24, 2018 Category: Transplant Surgery Authors: Lionaki S, Pappas A, Altanis N, Kapsia H, Liapis G, Vittoraki A, Iniotaki A, Zavos G, Boletis JN Tags: Exp Clin Transplant Source Type: research