A Pan-Cancer Landscape Analysis Reveals a Subset of Endometrial Stromal and Pediatric Tumors Defined by Internal Tandem Duplications of < b > < i > BCOR < /i > < /b >

Conclusion:BCOR-ITDs define a rare subset of pediatric sarcomas and clinically aggressive endometrial stromal sarcoma cases, as defined by NGS for the first time. Our findings help delineate the pan-cancer landscape of this alteration and suggest the need for focused investigation to delineate the pro-oncogenic function ofBCOR, along with any sensitivity to targeted therapies.Oncology
Source: Oncology - Category: Cancer & Oncology Source Type: research