Direct targeting of the mouse optic nerve for therapeutic delivery

ConclusionsWe successfully targeted the murine optic nerve intraorbitally, through the optic foramen, and transcranially. Of all methods, the injection through the optic foramen is likely the most innovative and fastest. These methods offer additional approaches for therapeutic intervention to be used by those studying white matter damage and axonal regeneration in the CNS.

Source: Journal of Neuroscience Methods - October 31, 2018 Category: Neuroscience Source Type: research