Letter: faecal calprotectin, clinical indices and the diagnosis of inflammatory bowel disease

Alimentary Pharmacology&Therapeutics,Volume 48, Issue 10, Page 1166-1166, November 2018.
Source: Alimentary Pharmacology and Therapeutics - Category: Drugs & Pharmacology Authors: Source Type: research

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Authors: Dalzell AM, Ba'Ath ME Abstract Inflammatory bowel disease (IBD) should be considered in any child with a persistently altered bowel habit. Growth failure may be a consequence and there may also be extra-intestinal manifestations. Oesophago-gastroduodenoscopy and colonoscopy and conventional histopathology are the diagnostic tools of choice in IBD. The identification and management of children with IBD in resource-poor settings is difficult and there are few data on its prevalence in low- and middle-income countries. The main challenges are a lack of resources and infrastructure including trained personnel ...
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research
Authors: Teng X, Xu L, Sun M, Guo J Abstract A retrospective analysis of the phenotypic characteristics, clinical manifestations, investigations and interleukin-10 receptor (IL-10R) status of inflammatory bowel disease (IBD) in infants and children under 2 years of age in Liaoning Province, China between January 2015 and October 2016 is described. Six patients without a family history of IBD were diagnosed with Crohn disease, and IL-10R mutations were detected in five of them. Compound heterozygous patients with IL-10R mutations had severe clinical manifestations, were resistant to standard medication for IBD ...
Source: Paediatrics and international child health - Category: Pediatrics Tags: Paediatr Int Child Health Source Type: research
Test your medicine knowledge with the  MKSAP challenge, in partnership with the American College of Physicians. A 49-year-old woman is evaluated for recently worsening joint symptoms. She has a 13-year history of Crohn disease characterized by four to six stools daily and mild crampy abdominal pain. She also has a 1-year history of ar thritis. She currently has […]Find jobs at  Careers by KevinMD.com.  Search thousands of physician, PA, NP, and CRNA jobs now.  Learn more.
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Conditions Gastroenterology Rheumatology Source Type: blogs
The objective of this report was to summarize current knowledge of CC, squamous intraepithelial lesions, and human papillomavirus (HPV) infection in non-HIV immunocompromised women to determine best practices for CC surveillance in this population and provide recommendations for screening. We evaluated those with solid organ transplant, hematopoietic stem cell transplant, and a number of autoimmune diseases. A panel of health care professionals involved in CC research and care was assembled to review and discuss existing literature on the subject and come to conclusions about screening based on available evidence and expe...
Source: Journal of Lower Genital Tract Disease - Category: OBGYN Tags: HPV-Associated Disease: Diagnosis and Management Source Type: research
Conclusions: The gastrointestinal mucosa presents unique mechanisms of immune tolerance towards nutrients and commensals under a delicate balance, which is nevertheless dysregulated in IBD. Counteracting this imbalance, dietary peptides carry a range of biological activities that might provide positive impact on gastrointestinal homeostasis. The anti-inflammatory, antioxidant and immunomodulatory properties of peptides from diverse food sources has been broadly evaluated in vitro. Protective mechanism of action through modulation of the pro-/anti-inflammatory and tolerogenic profile of immune responses has been demonstrate...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
Authors: Nielsen OH, Ainsworth MA, Steenholdt C PMID: 30895827 [PubMed - as supplied by publisher]
Source: Expert Review of Gastroenterology and Hepatology - Category: Gastroenterology Tags: Expert Rev Gastroenterol Hepatol Source Type: research
Authors: Jang HJ PMID: 30893984 [PubMed - in process]
Source: Gut and Liver - Category: Gastroenterology Tags: Gut Liver Source Type: research
Conditions:   Inflammatory Bowel Diseases;   Crohn Disease;   Ulcerative Colitis Intervention:   Biological: Infliximab or adalimumab or golimumab or vedolizumab or ustekinumab Sponsor:   Fundación de Investigación Biomédica - Hospital Universitario de La Princesa Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: May 2019Source: Molecular Immunology, Volume 109Author(s): Hongxing Shen, Lewis Zhichang ShiAbstractIL-17-producing TH17 cells have been associated with autoimmune diseases such as multiple sclerosis (MS), psoriasis, Crohn’s disease, and ulcerative colitis (Han et al., 2015), many of which lack effective therapies. Identifying effective approaches to selectively suppress TH17 cell development and function represents a legitimate strategy to cure these autoimmune disorders. TH17 cell differentiation requires rewiring of their metabolic program, transition from the oxidative phosphorylation-dominant c...
Source: Molecular Immunology - Category: Allergy & Immunology Source Type: research
This article presents the American College of Gastroenterology's updated guidelines on managing Crohn's disease in adult patients.U.S. Pharmacist
Source: Medscape Allergy Headlines - Category: Allergy & Immunology Tags: Pharmacist Journal Article Source Type: news
More News: Drugs & Pharmacology | Inflammatory Bowel Disease