Nuchal Rigidity in Infantile Bacterial Meningitis

A 1-year-old boy presented with a 2-day history of fever and vomiting. His vaccination status was up to date, including 4 doses of the 13-valent pneumococcal conjugate vaccines and Hemophilus influenza type b vaccines. At presentation, there were no physical signs suggesting respiratory or circulatory compromise. His heart rate and respiratory rate were 150 beats per minute and 44 times per minute, respectively. His body temperature was 39.6 °C. There was no paralysis, and the pupillary light reflex was normal.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Rediscovering the Physical Exam Source Type: research

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Experts in immunology, vaccine biology, biomedical engineering, optics and physics will use cutting-edge imaging technologies to watch the immune system work in real time and explore ways to better fight infections like the flu.
Source: University of Rochester Medical Center Press Releases - Category: Universities & Medical Training Authors: Source Type: news
Authors: Pu F, Feng J, Yang L, Zhang L, Xia P Abstract Compared to other diseases, early or atypical spinal tuberculosis (TB) is prone to being misdiagnosed due to the lack of specific clinical manifestations and misleading negative results of various laboratory analyses and imaging examinations. Various methods for diagnosing spinal TB have become research hotspots. Recently, it has been proposed that effective vaccination is a mainstay of long-term policies to combat and control the TB epidemic. However, some new TB vaccines require further evaluation and clinical trials to demonstrate their efficiency and safety...
Source: Experimental and Therapeutic Medicine - Category: General Medicine Tags: Exp Ther Med Source Type: research
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Source: Medecine et Maladies Infectieuses - Category: Infectious Diseases Tags: Med Mal Infect Source Type: research
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Source: IDCases - Category: Infectious Diseases Source Type: research
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Source: AAFP News - Category: Primary Care Source Type: news
We report the human induced pluripotent stem cell line (iPSC) CSUASOi002-A, generated from urine-derived cells (UCs) from a 51-year-old female patient carrying compound heterozygous mutations (c.62_63delTinsGA and c.C892T) in the carbohydrate sulfotransferase 6 gene (CHST6). This patient was from a Chinese family of three siblings with macular corneal dystrophy (MCD). Patient UCs were reprogrammed by electroporation using the episomal plasmids (OCT4, SOX2, KLF4, L-MYC, LIN28 and shP53). The human MCD-UiPS cell line CSUASOi002-A retained the disease-associated genotype, while expressed pluripotent stem cell markers and coul...
Source: Stem Cell Research - Category: Stem Cells Source Type: research
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Source: AAFP News - Category: Primary Care Source Type: news
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