Changes in health in the countries of the UK and 150 English Local Authority areas 19902016: a systematic analysis for the Global Burden of Disease Study 2016

Leading causes of age-adjusted years of life lost(YLL) in 2016 were ischaemic heart disease, lung cancers, cerebrovascular disease and COPD. Age-standardised rates of YLLs for all causes varied 2-fold between local areas in England according to levels of socioeconomic deprivation
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news

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Publication date: Available online 24 June 2019Source: The LancetAuthor(s): Maigeng Zhou, Haidong Wang, Xinying Zeng, Peng Yin, Jun Zhu, Wanqing Chen, Xiaohong Li, Lijun Wang, Limin Wang, Yunning Liu, Jiangmei Liu, Mei Zhang, Jinlei Qi, Shicheng Yu, Ashkan Afshin, Emmanuela Gakidou, Scott Glenn, Varsha Sarah Krish, Molly Katherine Miller-Petrie, W Cliff Mountjoy-VenningSummaryBackgroundPublic health is a priority for the Chinese Government. Evidence-based decision making for health at the province level in China, which is home to a fifth of the global population, is of paramount importance. This analysis uses data from the...
Source: The Lancet - Category: General Medicine Source Type: research
In this study, we estimated the avoidable mortality burden attributable to ambient air pollution in Tehran, and derived the economic impact associated with these health effects. Using PM2.5 data from ground-level air pollution measurements in Tehran, we estimated PM2.5 exposure for 349 neighborhoods in Tehran, by the Environmental Benefits Mapping and Analysis Program (BenMAP-CE). We considered five scenarios related to PM2.5 levels: an increase to 35 μg/m3; a reduction to 25 μg/m3; a reduction to 15 μg/m3; a reduction to 10 μg/m3 (the WHO's air quality guideline value); and a full roll-back, assuming a...
Source: Environmental Research - Category: Environmental Health Authors: Tags: Environ Res Source Type: research
CONCLUSION: Our findings do not suggest that COPD nor other common comorbidities are significantly associated with higher mortality in NSCLC patients. PMID: 31092081 [PubMed - as supplied by publisher]
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
CONCLUSION: Comorbid conditions are very common in patients with CVD, even in younger age groups. To ensure efficient and effective treatment, organisational adaptations may be required in the healthcare system to accommodate comorbid conditions in patients with CVD. PMID: 31064742 [PubMed - as supplied by publisher]
Source: The British Journal of General Practice - Category: Primary Care Authors: Tags: Br J Gen Pract Source Type: research
Yafei Tan1,2, Omer Van den Bergh2, Jiang Qiu1* and Andreas von Leupoldt2* 1Faculty of Psychology, Southwest University, Chongqing, China 2Health Psychology, KU Leuven, Leuven, Belgium Dyspnea is a prevalent interoceptive sensation and the aversive cardinal symptom in many cardiorespiratory diseases as well as in mental disorders. Especially the unpredictability of the occurrence of dyspnea episodes has been suggested to be highly anxiety provoking for affected patients. Moreover, previous studies demonstrated that unpredictable exteroceptive stimuli increased self-reports and electrophysiological responses of an...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Authors: Serveaux-Dancer M, Jabaudon M, Creveaux I, Belville C, Blondonnet R, Gross C, Constantin JM, Blanchon L, Sapin V Abstract The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is expressed mainly in the lung, and involves multiple pathways (such as NFκB, Akt, p38, and MAP kinases) that initiate and perpetuate an unfavorable proinflammatory state. Due to these numerous functional activities, RAGE is implicated in multiple diseases. AGER is a highly polymorphic gene, with polymorphisms or S...
Source: Disease Markers - Category: Laboratory Medicine Tags: Dis Markers Source Type: research
Patients in hospice or receiving palliative care often are found to be receiving numerous medications. While we all agree that deprescribing, in practice, is a good idea, it can be difficult to discern which medications to stop, and at what point in the disease process. This all-day preconference will provide guidance to hospice and palliative care practitioners on deprescribing, as taught by experts in each therapeutic area. Learn about slimming down medications for heart disease, COPD, metabolic syndrome, cancer and more.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
Authors: Mohammadian T, Ganji L Abstract Helicobacter pylori causes one of the most common infections in human populations. The role of this bacterium in chronic gastritis, gastric ulcer, gastric cancer, as well as extra-digestive diseases such as ischemic heart disease and chronic obstructive pulmonary diseases, is well known. Prevention and control of these diseases can occur by early diagnosis and eradication of H. pylori infection. At present, different methods have been established to detect H. pylori infection. The biopsy-based tests, which are known as invasive methods, such as rapid urease test and histolog...
Source: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy - Category: Microbiology Tags: Monoclon Antib Immunodiagn Immunother Source Type: research
AbstractThis paper estimates the regional contribution of high PM2.5 concentration and associated mortality using HYSPLIT back trajectory analysis in eight Indian cities during 2015 –2016. Health risk and mortality estimation were carried out using the Integrated Exposure Response function (IER) which was verified using our previous time series study in Delhi. Risk estimates from IER were observed to be slightly over-predicted (2.14%) when compared to health risk from time se ries study in Delhi. Health risk in the eight cities across the four seasons indicated higher chronic obstructive pulmonary disease (COPD), lun...
Source: Air Quality, Atmosphere and Health - Category: Environmental Health Source Type: research
Abstract There is evidence that local traffic density and living near major roads can adversely affect health outcomes. We aimed to assess the relationship between local road length, proximity to primary highways, and cause-specific mortality in the 1991 Canadian Census Health and Environment Cohort (CanCHEC). In this long-term study of 2.6 million people, based on completion of the long-form census in 1991 and followed until 2011, we used annual residential addresses to determine the total length of local roads within 200 m of postal code representative points and the postal code's distance to primary highways....
Source: Environment International - Category: Environmental Health Authors: Tags: Environ Int Source Type: research
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