Dietary patterns and non-alcoholic fatty liver disease in a Greek case-control study

Non-alcoholic fatty liver disease (NAFLD) is considered to be a potential new component of the metabolic syndrome (MetS) [1]. It is characterized by excessive flux of fatty acids (FA) and triglycerides (TG) accumulation in the liver, primarily activated by dietary factors, obesity and insulin resistance [2]. This results in increased inflammation and mitochondrial dysfunction in the liver, conditions that lead to fibrosis and cell apoptosis. Moreover, genetic and epigenetic factors, as well as gut microbiome dysfunction, further induce hepatic steatosis, inflammation and oxidative stress.

Source: Nutrition - October 29, 2018 Category: Nutrition Authors: Ioanna Panagiota Kalafati, Dimitra Borsa, Maria Dimitriou, Konstantinos Revenas, Alexander Kokkinos, George Dedoussis Source Type: research