Abiomed joins Protembis $10m Series A
Protembis said today it closed a $10 million Series A round, joined by cardiovascular device-focused Abiomed (NSDQ:ABMD), to support its embolic cerebral protection device. The round was joined by Abiomed, Aachen and Mönchengladbach GmbH’s Seed Fonds III and a number of family offices and angel investors, the Aachen, Germany-based company said. “Patient safety should always be our top priority. We see great potential in Protembis’ technology to make TAVI neurologically safer and thus enable TAVI to be used in an even larger patient population,” Abiomed chief technology officer Dr. Thorsten Siess said in a prepared statement. Protembis is developing the ProtEmbo embolic cerebral protection device designed to minimize the risk of embolic cerebral lesions during minimally invasive cardiovascular interventions. The system consists of a filter device designed to be introduced into the aortic arch to prevent embolic particles from migrating into the brain. “Literally every TAVI intervention leads to particle migration to the brain” co-managing director &co-founder Karl von Mangoldt said in a prepared release. “Recent clinical studies have shown that up to 9 percent of TAVI patients suffer a stroke” co-managing director &co-founder Conrad Rasmus said in a press release. Last July, Protembis said it plans to collaborate with the German Accelerator Life Sciences program as it looks to expand into the US and acceler...
Publication date: Available online 20 February 2020Source: Life SciencesAuthor(s): Mahsa Hassanipour, Mohammadreza Zarisfi, Vahid Ehsani, Mohammad AllahtavakoliAbstractLate treatment with tissue plasminogen activator (tPA) leads to reperfusion injury and poor outcome in ischemic stroke. We have recently shown the beneficial effects of local brain hypothermia after late thrombolysis. Herein, we investigated whether transient whole-body hypothermia was neuroprotective and could prevent the side effects of late tPA therapy at 5.5 h after embolic stroke. After induction of stroke, male rats were randomly assigned into four g...
Carotid endarterectomy (CEA) is a proven intervention for stroke risk reduction in symptomatic and asymptomatic patients. High-risk patients are often offered carotid stenting to minimize risk and to optimize outcomes. As a referral center for high-risk patients, we sought to evaluate and to analyze our experience with high-risk CEA patients.
Conditions: Stroke; Stroke Sequelae Intervention: Sponsors: Cliniques universitaires Saint-Luc- Université Catholique de Louvain; Centre Hospitalier Universitaire Dinant Godinne - UCL Namur; CHU Ambroise-Paré - Mons Recruiting
Condition: Acute Ischemic Stroke Intervention: Diagnostic Test: hypoperfusion-hypodensity mismatch Sponsor: University Hospital Muenster Completed
Condition: Stroke Interventions: Device: HD-tCES; Device: Sham HD-tCES; Other: Upper extremity rehabilitation Sponsors: Taipei Medical University; Ministry of Science and Technology, R.O.C (Taiwan); National Cheng Kung University Not yet recruiting
Condition: Stroke Intervention: Other: Transitional Care Stroke Intervention (TCSI) Sponsors: McMaster University; Heart and Stroke Foundation of Canada; Canadian Foundation for Healthcare Improvement; Hamilton Health Sciences Corporation; Central South Regional Stroke Network; Rehabilitative Care Alliance; Max Bell Foundation; Health Quality O ntario; Canadian Frailty Network; CorHealth Ontario; Ontario&n...
Conditions: Ischemic Stroke; Hemorrhagic Stroke Interventions: Device: BCI-FES dorsiflexion therapy; Behavioral: Physiotherapy one hour; Behavioral: Physiotherapy two hours Sponsor: University of California, Irvine Recruiting
This study aims to evaluate the safety and efficacy of performing mechanical thrombectomies in older adults.
The use of CTP along with MRA, CTA, and angiography presents unique pearls and pitfalls in the community hospital setting. We hypothesize that this pictorial review and analysis will reveal trends and issues unique to the community setting that have not been exposed in prior research with implications relevant to practice.
Mechanical thrombectomy has been established as the standard of care for LVO (large-vessel occlusion) acute ischemic stroke following the favorable results of several prominent studies. Current guidelines and a recent meta-analysis endorse both thrombectomy techniques of aspiration and stent retriever as comparably effective treatments. The present study was conducted at a community hospital, which was recently certified as a comprehensive stroke center, to evaluate the efficacy of aspiration vs.