NIDA-NIAAA 2018 Mini-Convention: Frontiers in Addiction Research

Media Advisory:  Society for Neuroscience satellite meeting explores notable research in addiction ranging from data science to early life adversity impact on substance use disorders to opioid receptor function and pain
Source: NIAAA News - Category: Addiction Authors: Source Type: news

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Conclusions: Pain-depression dyad is associated with higher odds of opioids prescribing during primary care visits. Future studies are needed to understand the complexity of these factors and identify effective strategies to prevent opioids addiction and overdose among patients with pain and depression.
Source: Journal of the American Board of Family Medicine - Category: Primary Care Authors: Tags: Brief Reports Source Type: research
PMID: 31298942 [PubMed - as supplied by publisher]
Source: The American Journal of Drug and Alcohol Abuse - Category: Addiction Authors: Tags: Am J Drug Alcohol Abuse Source Type: research
Conclusion: Although MOH, SUD, and PD populations have been evaluated in multiple sites with different levels of expertise, the study supported the presence of a specific constellation of personality in MOH patients including obsessive (perfectionist) and dysphoric characteristics, as well as good enough psychological resources. No similarities to drug-addicted and personality-disordered patients were found. Practitioners' careful understanding of the personality characteristics of MOH patients may be useful to provide a road map for the implementation of more effective treatment strategies and intervention programs. ...
Source: Pain Research and Management - Category: Anesthesiology Authors: Tags: Pain Res Manag Source Type: research
AbstractObjectiveOsteoporosis is a skeletal disease with decreased bone mass and alteration in microarchitecture of bone tissue, and these changes put patients in risk of bone fracture. As a common symptom of osteoporosis and complication of osteoporotic fracture, chronic pain is a headache for clinicians. Nonsteroidal anti ‐inflammatory drugs (NSAIDs), selective COX‐2 inhibitors and opioid drugs can temporarily reduce osteoporotic pain but have relevant side effects, such as addiction, tolerability and safety. The review summarized the recent advancements in the study of CB receptors in osteoporosis and osteoporot ic ...
Source: Journal of Pharmacy and Pharmacology - Category: Drugs & Pharmacology Authors: Tags: Review Source Type: research
Codependency robs us of a self and self-love. We’ve learned to conceal who we really are because we grew up pleasing, rebelling against, or withdrawing from dysfunctional parents. That sets us up for trauma. As adults, even if we’re successful in some areas, our emotional life isn’t easy. Looking for security and love, most of us struggle to get into or out of relationships. We may remain in unhappy or abusive relationships or try to make painful ones work. Many of us would be content just to find a reprieve from ongoing anxiety or depression. After the Breakup However, ending a relationship isn’t t...
Source: Psych Central - Category: Psychiatry Authors: Tags: Abuse Codependence Domestic Violence PTSD Trauma Violence & Aggression Abusive Relationship Estrangement Guilt no contact Traumatic Experience Source Type: news
(Binghamton University) The herb kratom is increasingly being used to manage pain and treat opioid addiction, but it's not safe to use as an herbal supplement, according to new research led by faculty at Binghamton University, State University of New York.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
A study published last month in the peer-reviewed journal  Addiction by researchers at the British Columbia Centre for Disease Control and the British Columbia Centre on Substance Use found that harm reduction strategies were responsible for the province ’s opioid-related overdose death rate being less than half of what it otherwise would have been between April 2016 and December 2017.The researchers noted that 77 percent of opioid-related overdose deaths during that time frame involved illicit fentanyl. Vancouver has long been a major port of entry for fentanyl and fentanyl analogs, produced in China and o...
Source: Cato-at-liberty - Category: American Health Authors: Source Type: blogs
AbstractPeople living with HIV (PLHIV) often experience pain for which opioid medications may be prescribed. Thus, these individuals are particularly vulnerable to opioid-related harms, including overdose, misuse, and addiction, particularly when prescribed at high doses. We used a comprehensive linked population-level database of PLHIV in British Columbia (BC) to identify demographic and clinical characteristics associated with being prescribed any high-dose opioid analgesic, defined as  >  90 daily morphine milligram equivalents (MME/day). Among PLHIV who were prescribed opioids between 1996 and 2015 (n&...
Source: AIDS and Behavior - Category: Infectious Diseases Source Type: research
This article reviews the role of analgesic drugs with a particular emphasis on opioids. Opioids are the oldest and most potent drugs for the treatment of severe pain, but they are burdened by detrimental side effects such as respiratory depression, addiction, sedation, nausea, and constipation. Their clinical application is undisputed in acute (e.g., perioperative) and cancer pain, but their long-term use in chronic pain has met increasing scrutiny and has contributed to the current opioid crisis. We discuss epidemiological data, pharmacological principles, clinical applications, and research strategies aiming at novel opi...
Source: Best Practice and Research Clinical Rheumatology - Category: Rheumatology Source Type: research
Notice NOT-TR-19-025 from the NIH Guide for Grants and Contracts
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding
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