Astragalus polysaccharides inhibit oxidation in high glucose-challenged or SOD2-silenced H9C2 cells

Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

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Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Metabolic syndrome (MetS) is defined as a group of metabolic disorders that together increase a person ’s chance of developing cardiovascular diseases, including stroke. The component disorders that comprise MetS are central obesity, high blood pressure, high blood sugar, high triglycerides, and low high-density lipoprotein cholesterol (HDL-C) [1]. Body mass index (BMI), waist circumference (WC), w aist-hip ratio (WHpR), and waist-height ratio (WHtR) are anthropometric indices that can be used to define abdominal obesity for MetS diagnosis [2].
Source: Primary Care Diabetes - Category: Primary Care Authors: Tags: Original research Source Type: research
AbstractPurpose of ReviewRecent advances in genomics provide opportunities for novel understanding of the biology of human traits with the goal of improving human health. Here, we review recent obesity and type 2 diabetes (T2D) –related genomic studies in African populations and discuss the implications of limited genomics studies on health disparity and precision medicine.Recent FindingsGenome-wide association studies in Africans have yielded genetic discovery that would otherwise not be possible; these include identification of novel loci associated with obesity (SEMA-4D,PRKCA,WARS2), metabolic syndrome (CA-10,CTNN...
Source: Current Diabetes Reports - Category: Endocrinology Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Publication date: Available online 10 September 2019Source: Trends in Food Science &TechnologyAuthor(s): Vemana Gowd, Naymul Karim, Mohammad Rezaul Islam Shishir, Lianghua Xie, Wei ChenAbstractBackgroundMetabolic syndrome (MetS) is defined as the cluster of metabolic disorders that consist of insulin resistance, hyperglycemia, dyslipidemia, central adiposity, and hypertension, which is associated with metabolic diseases (MD). Gut microbiota (GM) has a profound effect on human metabolism. The composition and function of GM play a critical role in MD, but the mechanisms have not been fully understood yet. Microorganisms ...
Source: Trends in Food Science and Technology - Category: Food Science Source Type: research
ConclusionsWe conclude the review by emphasizing missing knowledge gaps that remain and future research opportunities needed to implement FKBP51 as a drug target for stress-related obesity or T2D.
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
Authors: Pasquali R, Oriolo C Abstract Androgen excess is often associated with obesity states, at any age of life, because of changes in the pattern of secretion or metabolism of androgens and in their actions at the level of target tissues, particularly the adipose tissue. Androgen excess plays an important role in favouring the expansion of visceral fat, which characterize so-called visceral obesity. Moreover, there is evidence that the combination of androgen excess and obesity may favour the development of metabolic disorders, such as the metabolic syndrome and type 2 diabetes. In obese adolescent girls, andro...
Source: Frontiers of Hormone Research - Category: Endocrinology Tags: Front Horm Res Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
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