High seroprevalence of Babesia antibodies among Borrelia burgdorferi-infected humans in Sweden
In this study, the prevalence of antibodies against two Babesia spp. was investigated in a cohort of patients that were seropositive for Borrelia (B.) burgdorferi sensu lato (s.l.). Data were compared to a control group of healthy individuals. Sera were collected from 283 individuals residing in the southernmost region of Sweden, Skåne County. Almost one third of the sera were from patients with a confirmed seropositive reaction against B. burgdorferi s.l. All sera samples were assessed for IgG antibodies against Babesia (Ba.) microti and Ba. divergens by indirect fluorescent antibody (IFA) assays. Seropositive IgG titers for at least one of the Babesia spp. was significantly more common (p
Publication date: Available online 13 July 2020Source: Ticks and Tick-borne DiseasesAuthor(s): L.M. Weinmayr, D. Kanz, M. Eckenweiler, T. Bormann, D. Huzly, J. Bardutzky, A. Harloff
A Peninsula biotech company is supplying a set of parasite-fighting preclinical compounds to a startup created by one of the scientists who co-founded the company more than two decades ago. Kainomyx Inc. — launched by a Stanford University-connected team including scientist Jim Spudich, a winner of the prestigious Lasker Award — is targeting malaria, leishmaniasis and other parasitic diseases. Spudich was one of the founders of Cytokinetics Inc. (NASDAQ: CYTK), which is taking an equity stake…
It is well known that visceral fat tissue is an important source of the chronic inflammation that drives the onset and progress of all of the common age-related diseases. This is normally discussed in the context of excess visceral fat, given the high prevalence of overweight individuals in our modern society of cheap calories and too little exercise. Visceral fat encourages the creation of senescent cells and their inflammatory secretions, but also rouses the immune system to inflammation via a range of other mechanisms. Overweight individuals have a shorter, less healthy life with higher lifetime medical expenses as a re...
This week's fun case is from Dr. Tess Karre, one of our former clinical microbiology fellows. The following structures were seen in a hematoxylin and eosin stained small bowel biopsy. Identification?
The company is also looking to fast-track its opioid use disorder therapy, thanks to relaxed FDA guidelines.
Conclusion: The risk of severe maternal cardiac complications during pregnancy in women with congenital heart disease is low. In this largest analysis to date with a focus on parity in 307 women, the risk classification predicts the maternal outcome more than parity per se. If the first pregnancy is uneventful, the OR is 5.5 for an uneventful second pregnancy if CARPREG I and mWHO scores remain unchanged.Cardiology
(Tokyo University of Science) The need to first zero in on a blood group can delay blood transfusions in emergency situations, and this in turn can prove fatal. Thus, to speed up the process, a team of scientists from Tokyo University of Science, Japan, has developed a lab-on-a-chip device that can not only tell the blood type within five minutes but allows medical staff to read the results through simple visual inspections.
Ticks and the diseases they carry have long been recognized as health concerns, especially in the warmer months when ticks (and humans) are more active. Ticks wait on grass tips or shrubs to latch onto new hosts when they brush by. Most of the hosts are animals, but a few tick species do bite and feed on humans. While doing so, they can transmit bacteria and viruses through their saliva. But here’s what’s changing: Tick species are being found in a wider geographic range. The number of case reports of tick-borne illnesses is increasing. Scientists continue to identify new pathogens (bacteria and viruses that c...