Investigating disease severity in an animal model of concurrent babesiosis and Lyme disease.

Investigating disease severity in an animal model of concurrent babesiosis and Lyme disease. Int J Parasitol. 2018 Oct 24;: Authors: Bhanot P, Parveen N Abstract The incidence of babesiosis, Lyme disease and other tick-borne diseases has increased steadily in Europe and North America during the last five decades. Babesia microti is transmitted by species of Ixodes, the same ticks that transmit the Lyme disease-causing spirochete, Borrelia burgdorferi. B. microti can also be transmitted through transfusion of blood products and is the most common transfusion-transmitted infection in the U.S.A. Ixodes ticks are commonly infected with both B. microti and B. burgdorferi, and are competent vectors for transmitting them together into hosts. Few studies have examined the effects of coinfections on humans and those have had somewhat contradictory results. One study linked coinfection with B. microti to a greater number of symptoms of overall disease in patients, while another report indicated that B. burgdorferi infection either did not affect babesiosis symptoms or decreased its severity. Mouse models of infection that manifest pathological effects similar to those observed in human babesiosis and Lyme disease offer a unique opportunity to thoroughly investigate the effects of coinfection on the host. Lyme disease has been studied using the susceptible C3H mouse infection model, which can also be used to examine B. microti infection to understand pathological m...
Source: International Journal for Parasitology - Category: Parasitology Authors: Tags: Int J Parasitol Source Type: research

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Source: Mammalian Biology - Category: Biology Source Type: research
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Source: Life Sciences - Category: Biology Source Type: research
Publication date: 15 July 2019Source: Journal of Alloys and Compounds, Volume 793Author(s): Ye-Chan Kim, Ho-Jung Jeong, Soo Kyung Lee, Sung-Tae Kim, Jae-Hyung JangAbstractCu2ZnSn(S,Se)4 (CZTSSe) absorber layers with various S/(S + Se) ratios at the surface and in the bulk were synthesized to investigate the effect of the S/(S + Se) ratios on the formation of secondary phases in the CZTSSe absorber layer. The higher density ZnS and Cu2SnSe3 (CTSe) secondary phases were observed at the surface of the CZTSSe absorber layer when the S/(S + Se) ratios were 0.46 and 0.40 at the surface and in t...
Source: Journal of Alloys and Compounds - Category: Chemistry Source Type: research
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Source: Rheumatology International - Category: Rheumatology Source Type: research
Condition:   Anemia, Sickle Cell Intervention:   Drug: HBI-002 Sponsors:   Hillhurst Biopharmaceuticals, Inc.;   National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
CHAGAS DISEASE, a deadly parasitic disease that could cause sudden death, could be spread by ‘kissing bug’ insects - and a new case has recently been diagnosed. These are the signs and symptoms you should be watching out for. Are you at risk of the parasite?
Source: Daily Express - Health - Category: Consumer Health News Source Type: news
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Source: Parasitology International - Category: Parasitology Source Type: research
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Source: Fish and Shellfish Immunology - Category: Biology Source Type: research
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Source: eLife - Category: Biomedical Science Tags: Ecology Evolutionary Biology Source Type: research
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Source: EUROPA - Research Information Centre - Category: Research Source Type: news
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