Rapid detection of mcr-1 by recombinase polymerase amplification.

CONCLUSION: RPA detection based on the mcr-1 gene was successfully applied in our study. The plasmid-mediated mcr-1 gene conferring colistin drug resistance has a strong ability to spread, suggesting the need to further strengthen the detection of this resistance gene in surveillance. Therefore, we require more sensitive detection methods than have previously been available and the RPA assay established in this study meets these detection needs.
PMID: 30355422 [PubMed - as supplied by publisher]

Source: Journal of Medical Microbiology - October 24, 2018 Category: Microbiology Authors: Xu J, Wang X, Yang L, Kan B, Lu X Tags: J Med Microbiol Source Type: research