Benzofurans, benzoic acid derivatives, diterpenes and pyrrolizidine alkaloids from Peruvian Senecio

Publication date: December 2018Source: Phytochemistry Letters, Volume 28Author(s): Liliana Ruiz-Vásquez, Lastenia Ruiz Mesia, Matías Reina-Artiles, M. López-Rodríguez, J. González-Platas, Cristina Giménez, Raimundo Cabrera, Azucena González-ColomaAbstractSixteen compounds incluiding four benzofurans (1–4), three benzoic acid derivatives (6–8), one eremophilane (9), four diterpenes (10–13) and four pyrrolizidine alkaloids (14–17) were isolated from Senecio subcandidus, S. klugii and S. ayapatensis from Perú. Compounds 1–4 and 6–9 have not been previously reported as natural products. Their molecular structures were determined by NMR spectroscopic analysis, comparison with published NMR data and chemical transformations. The X-ray analysis of acetylated derivative 5 and compound 7 were also performed. Their insecticidal and antifungal activities were tested.Graphical abstractSixteen compounds from endemic plants of Peru were isolated and characterized. Their insecticidal and antifungal activities were tested.
Source: Phytochemistry Letters - Category: Chemistry Source Type: research