Antimicrobial resistance of major clinical pathogens in South Korea, May 2016 to April 2017: first one-year report from Kor-GLASS.
We describe results from the first year of operation of the Kor-GLASS from May 2016 to April 2017, comprising all non-duplicated clinical isolates of major pathogens from blood, urine, faeces and urethral and cervical swabs from six sentinel hospitals. Antimicrobial susceptibility tests were carried out by disk diffusion, Etest, broth microdilution and agar dilution methods. Among 67,803 blood cultures, 3,523 target pathogens were recovered. The predominant bacterial species were Escherichia coli (n = 1,536), Klebsiella pneumoniae (n = 597) and Staphylococcus aureus (n = 584). From 57,477 urine cultures, 6,394 E. coli and 1,097 K. pneumoniae were recovered. Bloodstream infections in inpatients per 10,000 patient-days (10TPD) were highest for cefotaxime-resistant E. coli with 2.1, followed by 1.6 for meticillin-resistant Sta. aureus, 1.1 for imipenem-resistant Acinetobacter baumannii, 0.8 for cefotaxime-resistant K. pneumoniae and 0.4 for vancomycin-resistant Enterococcus faecium. Urinary tract infections in inpatients were 7.7 and 2.1 per 10TPD for cefotaxime-resistant E. coli and K. pneumoniae, respectively. Kor-GLASS generated well-curated surveillance data devoid of collection bias or isolate duplication. A bacterial bank and a database for the collections are under development. PMID: 30352640 [PubMed - in process]
A nation-wide initiative has been established for antibiotic stewardship in an effort to reduce over-treatment and over-diagnosis of infections. In our Skilled Nursing Facility (SNF), there are minimal guidelines for ordering urinalyses (UAs) in patients suspected of urinary tract infections (UTIs). Chart review demonstrated that UAs were ordered without systematic guidelines. We designed a project to educate SNF staff on a diagnostic algorithm adapted from McGeer criteria for UTIs
Concerns of urinary tract infections (UTI) are widespread in long-term care (LTC) settings. Non-specific symptoms can lead to unnecessary testing and inappropriate antibiotic use. There have been numerous protocols developed to standardize diagnosis of UTIs, including the McGeer criteria. At our LTC facility, we initiated a modified McGeer criteria for ordering urinalyses (UA) and culture. Our project examines the knowledge retention of the complexities of urinary tract symptoms and the comfort level of nursing staff when communicating with providers.
A Deep Dive into Urinary Tract Infections
Conclusions IUC insertion can be safely performed by medical students in the operating room. Simulation-based skills curricula for medical students can be effectively implemented and achieve clinically relevant improvements in patient outcomes.
President Donald Trump said on Wednesday the United States may in the future have to restrict travel to Italy, South Korea and other countries due to outbreaks of the coronavirus but now was not the right time.
There is a run on masks and other protective equipment as concern over the coronavirus grows. U.S. forces in South Korea have raised their alert level to “high” after more than 1,200 infections were confirmed in that country with one American soldier testing positive. Meg Oliver reports.
Ribosomal RNAs in all organisms are methylated. The functional role of the majority of modified nucleotides is unknown. We systematically questioned the influence of rRNA methylation in Escherichia coli on a number of characteristics of bacterial cells with the help of a set of rRNA methyltransferase (MT) gene knockout strains from the Keio collection. Analysis of ribosomal subunits sedimentation profiles of the knockout strains revealed a surprisingly small number of rRNA MT that significantly affected ribosome assembly. Accumulation of the assembly intermediates was observed only for the rlmE knockout strain whose growth...
BOSTON (CBS) – The Centers for Disease control has cautioned that, based on current patterns, coronavirus is likely to become a global pandemic. With no approved vaccine or medication to treat it, that could ultimately result in overloaded healthcare systems. What is a pandemic? Simply put, a pandemic is a global, widespread outbreak of a new illness. Because it is new, people don’t have the ability to fight it and can be easily infected. The last pandemic to widely affect the United States was H1N1 flu in 2009. The worst pandemic in history was the Spanish flu outbreak in 1918 which killed 50 million people wo...
FDA says fast-food chain "engaged in a pattern of receiving and offering for sale adulterated fresh produce."
The latest outbreak was from November to December 2019 in Iowa, where 22 people were infected with E. coli. Twenty of them were interviewed, and each said they ate at one or more of 15 Jimmy John’s locations