Use of antifibrinolytics in pediatric cardiac surgery: where are we now?

Pediatric Anesthesia,Volume 0, Issue ja, -Not available-.
Source: Pediatric Anesthesia - Category: Anesthesiology Authors: Source Type: research

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Authors: Strieth S, Hagemann J, Hess M Abstract Transoral laser microsurgery (TLM) for treatment of laryngeal cancer has reduced temporary tracheotomies, increased organ preservation rates, and improved functional results. Gold standard for laser-based transoral resection of laryngeal cancer is the application of CO2 lasers. Oncologically safe radical resection and postoperative voice outcome must be weighed up individually. Angiolytic laser effects enable modification of the tumor micromilieu by targeted obliteration of microvessels and antagonization of angiogenesis with preservation of vibrating laryngeal tissue...
Source: HNO - Category: ENT & OMF Tags: HNO Source Type: research
Publication date: May 2020Source: Neurobiology of Stress, Volume 12Author(s): Delia Belelli, Derk Hogenkamp, Kelvin W. Gee, Jeremy J. LambertAbstractIn the 1980s particular endogenous metabolites of progesterone and of deoxycorticosterone were revealed to be potent, efficacious, positive allosteric modulators (PAMs) of the GABAA receptor (GABAAR). These reports were followed by the discovery that such steroids may be synthesised not only in peripheral endocrine glands, but locally in the central nervous system (CNS), to potentially act as paracrine, or autocrine “neurosteroid” messengers, thereby fine tuning ne...
Source: Neurobiology of Stress - Category: Neuroscience Source Type: research
This study evaluates parathyroidectomy outcomes in elderly patients.MethodsPrimary hyperparathyroidism patients having parathyroidectomy as listed in the 2005 –2017 ACS-NSQIP database were separated by age: ≤60, 61–79 and ≥80. Outcomes included complications, 30-day mortality, return to the OR, operating times, and hospital length of stay (LOS). Multivariable logistic regression was used to compare patients 61–79 and ≥80 to those ≤60. Patien ts ≤60 and ≥80 were propensity score matched using gender, race, BMI, smoking status, steroid use, modified frailty index (mFI), ASA class, procedur...
Source: World Journal of Surgery - Category: Surgery Source Type: research
This study examined the impact of a surgical prescription of epoetin (EPO) in contemporary total hip arthroplasty (THA).MethodsWe conducted a comparative study in a series of 1402 primary THAs performed in patients all having a pre-operative haemoglobin (Hb) level documented four to eight   weeks before THA surgery. In group A (647 hips), one subcutaneous injection of 40,000 IU EPO once a week for four weeks was prescribed at the discretion of anaesthetist during the pre-operative visit in patients with pre-operative Hb between 10 and 13 g/dl. In group S comprising the remaining 755 hips, an amended EPO...
Source: International Orthopaedics - Category: Orthopaedics Source Type: research
Publication date: Available online 10 December 2019Source: Practical Radiation OncologyAuthor(s): Stephanie M. Ntoukas, Tatiana Ritchie, Susan Awrey, David C. Hodgson, Normand Laperriere, Ryan Yee, Vijay Ramaswamy, Barbara-Ann Millar, Nathan Becker, Derek S. TsangAbstractPurposeAt our institution, a multifaceted approach is used to reduce general anesthetic (GA) use for children receiving photon radiation therapy (RT) as standard-of-care treatment. The purpose of this study was to evaluate the effectiveness of our methods.Methods and MaterialsPatients treated as part of the pediatric radiation therapy program from 2010 to ...
Source: Practical Radiation Oncology - Category: Cancer & Oncology Source Type: research
We examined the influence of periprocedural blood pressure (BP), especially critical BP drops, on 3-month functional outcome in stroke patients undergoing mechanical thrombectomy (MT) under general anaesthesia (GA).MethodsWe screened all patients with anterior circulation large vessel occlusion receiving MT under GA at our centre from January 2011 to June 2016 and selected those who had continuous invasive periinterventional BP monitoring. Clinical and radiological data were prospectively collected as part of an ongoing cohort study, monitoring data were extracted from electronic anaesthesia records. We used uni- and multi...
Source: Journal of Neurology - Category: Neurology Source Type: research
AbstractOptimal wound care is an essential component in the management of systemic sclerosis (SSc) digital ulcers (DUs). DU debridement has been suggested to reduce ulcer-related pain and improve tissue healing. However, only a minority of rheumatologists perform DU debridement, and there is no standard of care/protocol. Our objectives were to (i) evaluate the current evidence for the use of debridement in DU management and (ii) assess whether there are any specific protocols. A systematic literature review was performed searching the PubMed database (between 01/01/1950 –01/03/2019) in accordance with PRISMA guidelin...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
ConclusionSubstantial agreement exists among experts regarding many strong recommendations for the improvement of practice concerning the use of muscle relaxants and reversal agents during anaesthesia. In particular, the French Society of Anaesthesia and Intensive Care (SFAR) recommends the use of a device to monitor neuromuscular blockade throughout anaesthesia.
Source: Anaesthesia, Critical Care and Pain Medicine - Category: Anesthesiology Source Type: research
Publication date: January 2020Source: Anaesthesia &Intensive Care Medicine, Volume 21, Issue 1Author(s):
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Publication date: January 2020Source: Anaesthesia &Intensive Care Medicine, Volume 21, Issue 1Author(s):
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
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