USP20 (Ubiquitin-Specific Protease 20) Inhibits TNF (Tumor Necrosis Factor)-Triggered Smooth Muscle Cell Inflammation and Attenuates Atherosclerosis.

Conclusions- USP20 attenuates TNF- and IL-1β-evoked atherogenic signaling in SMCs, by deubiquitinating RIPK1, among other signaling intermediates.
PMID: 30354204 [PubMed - in process]

Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 1, 2018 Category: Cardiology Authors: Jean-Charles PY, Wu JH, Zhang L, Kaur S, Nepliouev I, Stiber JA, Brian L, Qi R, Wertman V, Shenoy SK, Freedman NJ Tags: Arterioscler Thromb Vasc Biol Source Type: research