Estrogen Inhibits LDL (Low-Density Lipoprotein) Transcytosis by Human Coronary Artery Endothelial Cells via GPER (G-Protein-Coupled Estrogen Receptor) and SR-BI (Scavenger Receptor Class B Type 1).

Conclusions- Estrogen significantly inhibits LDL transcytosis by downregulating endothelial SR-BI; this effect requires GPER. PMID: 30354216 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30354216?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 1, 2018 Category: Cardiology Authors: Ghaffari S, Naderi Nabi F, Sugiyama MG, Lee WL Tags: Arterioscler Thromb Vasc Biol Source Type: research