LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Regulates Smooth Muscle Contractility by Modulating Ca2+ Signaling and Expression of Cytoskeleton-Related Proteins.

Conclusions- These results identify a critical role for LRP1 in modulating vascular smooth muscle cell contraction by regulating calcium signaling events that potentially protect against aneurysm development. PMID: 30354243 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/30354243?dopt=Abstract

Source: Arteriosclerosis, Thrombosis and Vascular Biology - October 26, 2018 Category: Cardiology Authors: Au DT, Ying Z, Hernández-Ochoa EO, Fondrie WE, Hampton B, Migliorini M, Galisteo R, Schneider MF, Daugherty A, Rateri DL, Strickland DK, Muratoglu SC Tags: Arterioscler Thromb Vasc Biol Source Type: research