Associations of Cord Blood Leptin and Adiponectin with Children ’s Cognitive Abilities

Leptin and adiponectin are peptide hormones secreted by adipose tissue and the placenta that play a role in metabolism and possibly neurodevelopment (Masuzaki et al., 1997; Chen et al., 2006; Arnoldussen et al., 2014). Leptin receptors are distributed throughout the brain, and leptin acts in multiple brain regions that are important for cognition (Funahashi et al., 2003; Farr et al., 2006; Oomura et al., 2006; Morrison, 2009). In mice, short-term leptin infusions improved memory and learning (Farr et al., 2006; Oomura et al., 2006).

Source: Psychoneuroendocrinology - October 25, 2018 Category: Psychiatry Authors: Nan Li, Tye E Arbuckle, Gina Muckle, Bruce P Lanphear, Michel Boivin, Aimin Chen, Linda Dodds, William D Fraser, Emmanuel Ouellet, Jean R S éguin, Maria P Velez, Kimberly Yolton, Joseph M Braun Source Type: research