Using a personalized clinical decision support system for bromdihydrochlorphenylbenzodiazepine dosing in patients with anxiety disorders based on the pharmacogenomic markers

Human Psychopharmacology: Clinical and Experimental, EarlyView.
Source: Human Psychopharmacology: Clinical and Experimental - Category: Psychiatry Authors: Source Type: research

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CONCLUSIONS: These findings support the use of patient experiences and feedback to aide product development. In addition, post-9/11 veterans support the use of eScreening to assist health screening. However, evaluating the eScreening program in more diverse veteran groups and Veterans Affairs settings is needed to improve the generalizability of these findings to the larger veteran population. PMID: 32060553 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
DISCUSSION: This group, comprising the mothers of young children, is particularly interesting in view of the credit constraints experienced by younger households during the financial crisis in Ireland. Both sets of results are consistent with qualitative studies which have shown that mortgage difficulties can lead to depression, anxiety and poor mental health, and that high status groups experience shame and self-blame when they experience a financial loss. It remains to be seen if this will have a long-term effect on the mental health of either the mothers or their children. PMID: 32060231 [PubMed - in process]
Source: Journal of Mental Health Policy and Economics - Category: Psychiatry Tags: J Ment Health Policy Econ Source Type: research
AbstractAccumulating evidence indicates that disruption of galanin signaling is associated with neuropsychiatric disease, but the precise functions of this neuropeptide remain largely unresolved due to lack of tools for experimentally disrupting its transmission in a cell type-specific manner. To examine the function of galanin in the noradrenergic system, we generated and crossed two novel knock-in mouse lines to create animals lacking galanin specifically in noradrenergic neurons (GalcKO –Dbh). We observed reduced levels of galanin peptide in pons, hippocampus, and prefrontal cortex ofGalcKO –Dbh mice, indica...
Source: Anatomy and Embryology - Category: Anatomy Source Type: research
ConclusionsAmong uninsured and underinsured asthma patients with GAD and/or MDD who were initiated on a single antidepressant, those who were titrated to achieve target doses had reduced risk of severe asthma exacerbations and lower number of asthma ‐related outcomes than those who were not optimized to achieve target doses.
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - Category: Drugs & Pharmacology Authors: Tags: ORIGINAL RESEARCH ARTICLE Source Type: research
Publication date: Available online 16 February 2020Source: Journal of Psychiatric ResearchAuthor(s): Carisha S. Thesing, Mariska Bot, Yuri Milaneschi, Erik J. Giltay, Brenda W.J.H. PenninxAbstractBackgroundTemporality of the association of low omega-3 polyunsaturated fatty acid (n-3 PUFA) plasma levels with depression remains questionable. To determine the underlying nature of these associations, this study examined the bidirectional longitudinal associations of n-3 PUFA plasma levels with (presence, onset and course of) depressive disorders and symptoms.MethodsBaseline (n = 2912, 28.6% with current depressive disorder...
Source: Journal of Psychiatric Research - Category: Psychiatry Source Type: research
Publication date: Available online 11 February 2020Source: NeuroscienceAuthor(s): Georgia Watt, Magdalena Przybyla, Valeria Zak, Janet van Eersel, Arne Ittner, Lars M. Ittner, Tim KarlAbstractAlzheimer’s disease (AD) is a neurodegenerative disease characterized by progressive cognitive decline and the accumulation of two hallmark proteins, amyloid-beta (Aβ) and tau. Traditionally, transgenic mouse models for AD have generally focused on Aβ pathology, however, in recent years a number of tauopathy transgenic mouse models have been developed, including the TAU58/2 mouse model. These mice develop tau pathology...
Source: Neuroscience - Category: Neuroscience Source Type: research
Publication date: Available online 16 February 2020Source: Journal of Clinical NeuroscienceAuthor(s): Sevda Korkmaz, Denizhan Danacı Keleş, Aslı Kazgan, Sema Baykara, Mehmet Gürkan Gürok, Caner Feyzi Demir, Murad AtmacaAbstractAimBased on our clinical observations, low emotional intelligence level and problem-solving skills may have play a role in suicide attempts. The present study is aimed to investigate the emotional intelligence levels and the correlation between problem solving skills and suicide attempts in individuals who already attempted suicide.Material and methodThe study was conducted on twenty-fiv...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
The best marital investment you can make takes just 21 minutes a year. → Support PsyBlog for just $5 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Relationships subscribers-only Source Type: blogs
Adding this ingredient to your diet could halve the risk of dying from a heart attack or stroke. → Support PsyBlog for just $5 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Heart Disease Source Type: blogs
Both techniques lead to people losing 5 percent of their body weight. → Support PsyBlog for just $5 per month. Enables access to articles marked (M) and removes ads. → Explore PsyBlog's ebooks, all written by Dr Jeremy Dean: Accept Yourself: How to feel a profound sense of warmth and self-compassion The Anxiety Plan: 42 Strategies For Worry, Phobias, OCD and Panic Spark: 17 Steps That Will Boost Your Motivation For Anything Activate: How To Find Joy Again By Changing What You Do
Source: PsyBlog | Psychology Blog - Category: Psychiatry & Psychology Authors: Tags: Weight Loss Source Type: blogs
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