In Vitro Assessment of Potential for CYP-Inhibition-Based Drug –Drug Interaction Between Vonoprazan and Clopidogrel

ConclusionsThe body of evidence shows that the pharmacodynamic DDI reported between vonoprazan and clopidogrel is unlikely to be caused by the inhibition of CYP2B6, CYP2C19, or CYP3A4/5 by vonoprazan.

Source: European Journal of Drug Metabolism and Pharmacokinetics - October 25, 2018 Category: Drugs & Pharmacology Source Type: research