iCAD touts clinical results with Xoft Axxent brachytherapy

iCAD is highlighting positive clinical results for its Xoft Axxent electronic...Read more on AuntMinnie.comRelated Reading: iCAD highlights study results of DBT software FDA OKs iCAD's breast density AI software iCAD touts study on radiation therapy savings iCAD scores Chinese OK for balloon applicators iCAD to highlight Xoft clinical results at AAPM
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news

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To compare a standard radio-oncological and a surgical biochemical failure definition after combined-modality radiation therapy (CRT) in men with intermediate- and high-risk prostate cancer.
Source: Brachytherapy - Category: Cancer & Oncology Authors: Source Type: research
The objective function considers pairs of dose points and each pair is given a distance-based penalty if the dose is either too high or too low at both dose points. Constraints are included to retain dosimetric indices at acceptable levels. Our model is designed to automate the manual adjustment step in the planning process. In the automatic adjustment step large-scale optimization models are solved. We show reductions of the volumes of the largest hot and cold spots, and the computing times are feasible in clinical practice. PMID: 31610533 [PubMed - as supplied by publisher]
Source: Physics in Medicine and Biology - Category: Physics Authors: Tags: Phys Med Biol Source Type: research
We report here oncological outcomes and toxicity of hypofractionated breast irradiation. After defining the frame of moderate and extreme hypofractionated breast irradiations based on overall treatment time, patient selection criteria were listed. According to their levels of proof, the results of moderate and extreme hypofractionated breast irradiation were analysed. Overall treatment time for moderate hypofractionated breast irradiation ranged from 3 to 4 weeks, while for extreme hypofractionated breast irradiation, it was less than 1 week. For moderate hypofractionated breast irradiation, whole breast irradiation w...
Source: Cancer Radiotherapie - Category: Cancer & Oncology Authors: Tags: Cancer Radiother Source Type: research
Older patients undergoing radiation therapy (RT) for pelvic malignancies are at increased risk for pelvic fracture, which is associated with significant morbidity and mortality. RT techniques such as brachytherapy or intensity modulated RT (IMRT) allow for more conformal dose distributions, but it is not known whether the risk for pelvic fracture varies by RT modality.
Source: International Journal of Radiation Oncology * Biology * Physics - Category: Radiology Authors: Source Type: research
CONCLUSIONS: Higher dose volumes for the bladder and rectum predicted for poorer PR-QOL. In contrast to prostate brachytherapy data, neither prostate volume nor urethral dosimetry at this dose schedule correlated with urinary symptoms. PMID: 31584457 [PubMed - as supplied by publisher]
Source: Clinical Prostate Cancer - Category: Cancer & Oncology Authors: Tags: Am J Clin Oncol Source Type: research
This article gives a tutorial on basic therapeutic medical physics. Medical health physics dealing with the issue of radiation protection for personnel and the public in the radiation environment is explained first. Next, we introduce the concept of absorbed dose related to energy deposition in tissues and then dosimetry instrumentation. Three-dimensional treatment planning systems that are now an integral component of modern radiation therapy are described. External beam radiation therapy, particle beam radiation therapy, and brachytherapy are briefly described. The change in quality assurance for contemporary radiation t...
Source: Hematology/Oncology Clinics of North America - Category: Cancer & Oncology Authors: Source Type: research
In conclusion, high-risk patients with risk factors such as laparoscopic surgery, harvesting more than 30 pelvic lymph nodes, PALND, and adjuvant pelvic EBRT require closer observation for LEL.
Source: Cancers - Category: Cancer & Oncology Authors: Tags: Article Source Type: research
Brachytherapy (BT) is widely used for salvage therapy in patients with biochemical failure (BF) after radiotherapy for prostate cancer (PCa). Although low-dose-rate (LDR) and high-dose-rate (HDR) BT are both used for salvage therapy, it is not clear whether there are any differences between these two approaches in terms of efficacy or toxicity in this setting. Therefore, we review the institutional experience of the members of the Urological Tumour Working Group (URONCOR) of the Spanish Society of Radiation Oncology (SEOR) to compare these two techniques.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Technical Note Source Type: research
A, Sancho Pardo G, Zapatero A, Álvaro PC Abstract BACKGROUND: Brachytherapy (BT) is widely used for salvage therapy in patients with biochemical failure (BF) after radiotherapy for prostate cancer (PCa). Although low-dose-rate (LDR) and high-dose-rate (HDR) BT are both used for salvage therapy, it is not clear whether there are any differences between these two approaches in terms of efficacy or toxicity in this setting. Therefore, we review the institutional experience of the members of the Urological Tumour Working Group (URONCOR) of the Spanish Society of Radiation Oncology (SEOR) to compare these two te...
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - Category: Radiology Authors: Tags: Radiother Oncol Source Type: research
There is now clear evidence of improved biochemical disease free survival (bDFS) with radiotherapy dose-escalation in all prostate cancer (PCa) risk groups [1,2]. Despite the advent of new techniques, external beam radiotherapy (EBRT) is limited in dose escalation due to the continuous change in the position, shape and volume of the target volume as well as the organs at risk (OARs). High-dose-rate brachytherapy (HDR) is a recommended treatment of eligible patients with prostate cancer as a method of dose escalation in conjunction with external beam radiation therapy according to the American Society of Clinical Oncology&a...
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Original Article Source Type: research
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