Cystic Fibrosis: Advancing Along the Continuum
Cystic fibrosis (CF) is an autosomal recessive genetic disorder resulting from a mutation in the gene which encodes a cellular transmembrane protein channel known as the CF transmembrane conductance regulator. Located systemically on the surface of numerous cells, these altered channels yield multisystem dysfunction. Typical manifestations seen are chronic, progressive, obstructive lung disease, pancreatic insufficiency, CF-related diabetes mellitus, malabsorption and malnutrition, liver disease, and infertility.
Source: Journal of Pediatric Health Care - Category: Pediatrics Authors: Francine Bono-Neri, Cara Romano, Anne Isedeh Tags: Article Source Type: research
More News: Cystic Fibrosis | Diabetes | Diabetes Mellitus | Endocrinology | Genetics | Health Management | Infertility | Liver | Liver Disease | Pancreas | Pediatrics | Reproduction Medicine | Urology & Nephrology